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Depression in Adults Who Are Overweight or Obese

04/09/2020

In an analysis of primary care records of 519,513 UK adults who were overweight or obese between 2000–2016 and followed up until 2019, the incidence of new cases of depression was 92 per 10,000 people per year. The risk of depression also rose with higher weight, according to the Obesity analysis.

In an analysis of primary care records of 519,513 UK adults who were overweight or obese between 2000–2016 and followed up until 2019, the incidence of new cases of depression was 92 per 10,000 people per year. The risk of depression also rose with higher weight, according to the Obesity analysis.

The study also found that antidepressants were prescribed in approximately two-thirds of adults who were overweight or obese.  Prescriptions for fluoxetine dropped over time (from 20.4% in 2000 to 8.8% in 2018) and prescriptions for sertraline increased (from 4.3% in 2000 to 38.9% in 2018).

“Our findings highlight the complex relationship between depression and obesity,” said lead author Freya Tyrer, of the University of Leicester, in the UK. “We would like to see tailored guidance on antidepressant prescribing and services that focus on both mood and behaviors to improve outcomes for these individuals.”

Additional Information

Link to Study: https://onlinelibrary.wiley.com/doi/10.1002/oby.22772

About Journal 

Obesity is owned by and is the official publication of The Obesity Society. The journal offers prompt publication of high-quality original research and presents new information in the areas of clinical nutrition medicine, pharmacology, nutrition medicine, genetics, adipogenesis, behavioral epidemiology, biophysics and lipid metabolism, exercise and human physiology, nutritional epidemiology, phenotyping, fat cell physiology, aging, neuroscience, transgenic models, metabolic syndrome, nutrition behavior, pediatric obesity, and adipocyte cell biology.

About Wiley

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Penny Smith +44 (0) 1243 770448 (UK)
newsroom@wiley.com

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