Individuals who are obese often experience heartburn and other symptoms of acid reflux. Previous research indicates that gastric bypass surgery for obesity helps alleviate symptoms in the short term, but a new Alimentary Pharmacology & Therapeutics study finds that these benefits often are not long-lasting.
Individuals who are obese often experience heartburn and other symptoms of acid reflux. Previous research indicates that gastric bypass surgery for obesity helps alleviate symptoms in the short term, but a new study finds that these benefits often are not long-lasting.
In the Alimentary Pharmacology & Therapeutics study of 2454 patients (mostly women) who had surgery for obesity and who were also taking medicines for acid reflux, symptoms of acid reflux improved in most patients shortly after surgery, but they returned in almost half of all patients within 2 years. Symptoms were more likely to return in women, older individuals, and those with other serious medical problems.
“Physicians and patients should be aware of the limited effect of gastric bypass on reflux in patients with severe obesity, particularly in those with risk factors for post‐operative reflux,” the authors wrote.
Additional Information
Link to Study: https://onlinelibrary.wiley.com/doi/10.1111/apt.15274
About Journal
Alimentary Pharmacology & Therapeutics is an international journal of gastroenterology and hepatology.
The journal accepts systematic reviews, meta-analyses, randomised controlled trials and original papers concerned with Gastroenterology and Hepatology.
AP&T is particularly interested in therapies and diagnostics, including all aspects of translation from bench to bedside: identification of novel therapeutic targets, epidemiology, clinical trials, drug safety and meta-analyses.
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