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Precision Medicine Test May Help Detect Coronary Artery Disease

12/06/2017

In a Journal of the American Geriatrics Society study, a blood-based precision medicine test incorporating age, sex, and gene expression score (ASGES) was helpful in evaluating older outpatients with symptoms suggestive of obstructive coronary artery disease (CAD).

 

In a Journal of the American Geriatrics Society study, a blood-based precision medicine test incorporating age, sex, and gene expression score (ASGES) was helpful in evaluating older outpatients with symptoms suggestive of obstructive coronary artery disease (CAD).

In the study of 176 stable, non-acute outpatients presenting with symptoms suggestive of obstructive CAD who were aged 65 and older, participants with low scores with low likelihood of obstructive CAD were referred for further evaluation at low rates, whereas those with higher scores had higher rates of referral to cardiology and advanced cardiovascular tests. At 1-year follow-up, the incidence of major adverse cardiovascular events or revascularization was higher in participants with high ASGES than in those with low ASGES (10 percent versus 0 percent). 


Additional Information

Link to Study: http://onlinelibrary.wiley.com/doi/10.1111/jgs.15215/full

About Journal

Included in more than 9,000 library collections around the world, JAGS is the go-to journal for clinical aging research. We provide a diverse, interprofessional community of healthcare professionals with the latest insights on geriatrics education, clinical practice, and public policy—all supporting the high-quality, person-centered care essential to our well-being as we age

Our rigorous peer-review process ensures that we bring healthcare professionals, older adults, and caregivers research with the potential to impact public policy and geriatrics care today—and tomorrow. Since the publication of our first edition in 1953, JAGS has remained one of the oldest and most impactful journals dedicated exclusively to gerontology and geriatrics.

Penny Smith
Tel: +44 (0)1243 770448
sciencenewsroom@wiley.com

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