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Plant-Derived Products May Help Fight HBV

01/17/2017

Researchers have found that certain plant-derived products may help prevent and treat hepatitis B virus (HBV) infection. Proanthocyanidin (PAC) and its analogs, oolonghomobisflavanes, act by inhibiting viral entry into host cells.

Researchers have found that certain plant-derived products may help prevent and treat hepatitis B virus (HBV) infection. Proanthocyanidin (PAC) and its analogs, oolonghomobisflavanes, act by inhibiting viral entry into host cells.

The investigators noted that PAC was effective even against treatment-resistant HBV strains, and it augmented the ability of the antiviral drug tenofovir to interrupt HBV spread in human cells.

“PAC represents a specific inhibitor against HBV that is a less toxic plant-derived agent used as a dietary supplement,” said Dr. Koichi Watashi, co-author of the Hepatology study.


Additional Information: 

Link to study: http://onlinelibrary.wiley.com/doi/10.1002/hep.28952/abstract

About Journal

Hepatology is the premier publication in the field of liver disease, publishing original, peer-reviewed articles concerning all aspects of liver structure, function and disease. Hepatology’s current impact factor is 10.885.Each month, the distinguished Editorial Board monitors and selects only the best articles on subjects such as immunology, chronic hepatitis, viral hepatitis, cirrhosis, genetic and metabolic liver diseases and their complications, liver cancer, and drug metabolism. Hepatology is published on behalf of the American Association for the Study of Liver Diseases (AASLD). For more information, please visit http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1527-3350.

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