A new article published in Environmental Toxicology and Chemistry looks under the hood of how US Environmental Protection Agency (EPA) scientists develop and validate testing methods that support regulatory decisions.
A new article published in Environmental Toxicology and Chemistry looks under the hood of how US Environmental Protection Agency (EPA) scientists develop and validate testing methods that support regulatory decisions.
The work focuses on how the EPA developed tests to assist in the prioritization and risk assessment of endocrine disrupting chemicals. The Endocrine Disruptor Screening Program uses a tiered testing strategy to determine the potential of pesticides, commercial chemicals, and environmental contaminants to disrupt the endocrine system, specifically in relation to estrogen, androgen, and thyroid hormones.
“The finalized test method is a product of several years of productive collaboration between EPA scientists and our colleagues at the Ministry of the Environment in Japan,” said Kevin Flynn, lead author of the article.
flynn.kevin@epa.gov
Summary of the Development the US Environmental Protection Agency’s Medaka Extended One Generation Reproduction Test (MEOGRT) Using Data from Nine Multigenerational Medaka Tests
Additional Information
Link to Study: http://onlinelibrary.wiley.com/doi/10.1002/etc.3923/full
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Environmental Toxicology and Chemistry publishes papers describing original experimental or theoretical work that significantly advances understanding in the area of environmental toxicology, environmental chemistry, and hazard/risk assessment. ET&C is interdisciplinary in scope and integrates the fields of environmental toxicology; environmental, analytical, and molecular chemistry; ecology; physiology; biochemistry; microbiology; genetics; genomics; environmental engineering; chemical, environmental, and biological modeling; epidemiology; and earth sciences.
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