Researchers have found that smoking may increase the risk of dying early in premenopausal women with breast cancer.
Researchers have found that smoking may increase the risk of dying early in premenopausal women with breast cancer.
In a prospective study of 848 women with breast cancer who were followed for a median of 6.7 years, premenopausal women who smoked for more than 21.5 years had a 3.1-times higher risk of dying from any cause as well as a 3.4-times higher risk of dying from breast cancer. These links were not apparent among post-menopausal women.
There was also some suggestion that the increased risks seen in premenopausal women were especially relevant to women whose cancers expressed both the estrogen receptor and the progesterone receptor.
“Overall, this work is monumental in advising patients about how their smoking might affect their outcome,” said Dr. Yuko Minami, co-author of the Cancer Science study. “Hopefully this paper will serve to reduce the number of breast cancer patients who continue to smoke.”
This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as an ‘Accepted Article’, doi: 10.1111/cas.12716
Additional Information
Full Citation: Kakugawa, Yoichiro, Kawai, Masaaki, Nishino, Yoshikazu, Fukamachi, Kayoko, Ishida, Takanori, Ohuchi, Noriaki, Minami, Yuko TI. Smoking and survival after breast cancer diagnosis in Japanese women: A prospective cohort study DOI: 10.1111/cas.12716 CANCER
Link to study: http://onlinelibrary.wiley.com/doi/10.1111/cas.12716/abstract
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